LC/MS Data Reduction & Analysis Software
BioAnalyte's powerful, yet easy-to-use, software applications: ProTrawler, Regatta, and MSRedux, were designed to overcome the limits of vendor-supplied software. They can be used together or separately.
ProTrawler™: LC/MS Data Reduction & Analysis Software
Automate analysis of your raw, unexported LC/MS and LC/MS/MS chromatograms. (No compliance problems with 21CFR11 rules). ProTrawler's fully automated batch design allows you to lock, load, and walk away.
Increase throughput, detection sensitivity, processing consistency, and mass accuracy. Get results in hours instead of the weeks it can take with instrument-vendor supplied software.
Break free from size limits: ProTrawler lets you analyze molecules to over 60k Da.
Use your existing computer hardware (no need to upgrade to expensive server technology).
ProTrawler benefits:
- Fast. Faster LC/MS data reduction in ProTrawler. We are 100x faster than MaxEnt or any other Bayesian method. How? Because we are 100x smarter in our approach.
- Sensitive. ProTrawler is at the signal-to-noise limit for sensitive extraction of features from data. We see 1000 fold intensity variability in the same m/z scan. The results are real, and you'll see for yourself because . . .
- Obvious. ProTrawler highlights the extracted features all of the way back to the raw data for that warm-and-fuzzy feeling that the results are real.
- Automatable. Load many chromatograms. Load a relevant ProTrawler model file. Press "Play" and come back when the numbers have been crunched.
- Optimizable. There isn't one aspect of model design in ProTrawler that isn't available to the expert user.
Regatta™: Multivariate, Comparative Analysis
Ideally suited for high-throughput labs, Regatta extends ProTrawler's capability to compare many chromatograms, of any size.
Regatta is a label-free quantitation tool kit, facilitating LC/MS alignment, dynamic binning, hierarchical clustering and principal component analysis for expression regulation.
"BioAnalyte's applications enhance bottom-up proteomics by showing the statistical significance of potential biomarkers. ProTrawler and Regatta more than just complement bottom-up proteomics; they give sequence ID quantitative meaning. And they are metabolomics-ready, as most of the existing mass spectrometry products are not." Kevin Jones, software4Labs.
Regatta benefits:
- Discerning. Regatta solves the "Is this the same as that?" problem, as well as the "What's the most important difference?" question.
- Qualitative. Be qualitative with Regatta's Hierarchical Cluster Analysis for presence/absence biomarker discovery.
- Quantitative. Be quantitative with Regatta's Principal Component Analysis for up/down regulated biomarker discovery.
- Relevant. Regatta avoids comparing apples to oranges with a disciplined approach to data comparison featuring Coefficients of Variation Filtering.
- Supported. BioAnalyte is available for customer report generation for either ProTrawler or Regatta.
MSRedux™: Rapidly Developed Custom Mini-Applications
An MS data reduction development service to help bench chemists drive decisions. If you are doing many runs of an experiment with different samples, this will fully automate the data processing and analysis, giving you one click from raw data to a data point for your analysis.
These mini-apps have the look-and-feel of simple printer drivers, but they do powerful raw data interpretation. Because they handle raw data, they can be used in place of instrument vendor-supplied software. Put raw data and a few parameters in. Take PDF figures and Excel spreadsheets out.
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Microtiter Ion Monitor:
An MSRedux application designed specifically for the IonSense DART technology.